Post menopausal hormonal replacement therapy Estero gen alone increases the risk whereas if it is combined with progesterone then there is hardly any risk so it should ideally be taken in combined firm. Obesity Fat in the body is the source of excess of esterogen especially in post menopausal females. This excess estero gen increases […]
Integration of Molecular Subtypes in Endometrial Carcinoma (Uterus Cancer)
Clinical Significance The integration of molecular classification into clinical practice has become pivotal for the risk stratification of endometrial carcinoma (EC). Key guidelines and systems, such as those from the World Health Organization (WHO), European Society of Gynaecological Oncology (ESGO), and others, now emphasize the relevance of molecular subtypes in managing EC. This approach offers […]
How to Prevent Endometrial Cancer (Uterus Cancer)
1. Use of Hormonal contraceptives Estrogen alone increases the risk of endometrial cancer because of its proliferative effect but combination with progestin decreases the risk of endometrial cancer by 30 to 40% and progestin only pill has much more protective effect. This protective effect persists for many years. 2. More the number of pregnancies more […]
Histologic Types of Endometrial Carcinoma (Uterus Cancer)
The World Health Organization (WHO) classifies endometrial carcinoma (EC) into several histological subtypes, each with distinct characteristics and implications for diagnosis and treatment. 1. Endometrioid Carcinoma Prevalence: Endometrioid carcinoma is the most common form, representing 75-80% of all EC cases. Histopathology: This type features tall columnar cells that line closely packed glands, often without intervening […]